Probiotics as Therapeutics

Probiotics in Clinical Practice as Therapeutics against Enteric Disorders

Review Article Probiotics as therapeutics for the developing world

Although described for over a century, scientists and clinicians alike are only now beginning to realize the significant medical applications of probiotics. Probiotic research in the developed world has received significant attention in recent years; however, the potential for probiotics in the developing world has remained relatively unexplored. This review focuses on the most recent advances ...

From probiotics to therapeutics: another step forward?

Preclinical studies with probiotics continue to unravel mechanisms of cytoprotection and suggest that approaches utilizing microbial products as therapeutics in acute and chronic gastrointestinal disorders could be effective. However, clinical trials using these bacteria have thus far been inconsistent. In this issue of the JCI, Yan et al. describe a novel mechanism of cytoprotection by p40, a ...

A systematic review of gold nanoparticles as novel cancer therapeutics

Objective(s):The current systematic study has reviewed the therapeutic potential of gold nanoparticles as nano radiosensitizers for cancer radiation therapy.   Materials and Methods: This study was done to review nano radiosensitizers. PubMed, Ovid Medline, Science Direct, SCOPUS, ISI web of knowledge, Springer databases were searched from 2000 to September 2013 to identify appropriate studies....

Proteases as therapeutics.

Proteases are an expanding class of drugs that hold great promise. The U.S. FDA (Food and Drug Administration) has approved 12 protease therapies, and a number of next generation or completely new proteases are in clinical development. Although they are a well-recognized class of targets for inhibitors, proteases themselves have not typically been considered as a drug class despite their applic...